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Tapentadol: A Look at It

Pain from an accident or treatment is one type of acute pain that this medicine is used to treat. This is an opioid, which is a type of medicine. Because it changes the brain, it changes how the body feels and handles pain.

How to Take and Use Tapentadol

This is what you should read every time you get a new prescription of tapentadol and before you start taking it. Talk to your doctor or the shop if you are worried about anything.

Do what your doctor tells you and take this medicine by mouth. You can take this medicine with or without food. Taking this medicine with food might help if you feel like you want to throw up. Do not move your head much while you lie down for an hour or two. Ask your doctor or pharmacist about other ways to treat sickness.

Dosage is based on how healthy the person is and how well the medicine is working. If you take too much or use it for too long, don’t do it. Your doctor told you to stop taking the medicine.

Pain killers work best when taken as soon as the pain starts. The medicine might not work as well if you wait until the pain gets worse before going to the doctor.

There are some things that might happen if you suddenly stop taking this medicine. This is especially true if you’ve been taking it for a long time or in large amounts. So that you don’t go through withdrawal, your doctor may change your amount slowly. Feeling tense, having trouble sleeping, or having suicidal thoughts? Tell your doctor or pharmacist right away. Also, let them know if your eyes are watering, your nose is stuffy, you have diarrhea or sickness, or if your behavior changes quickly.

This medicine might not work as well after a long time of use. Talk to your doctor if this medicine stops working right.

This medicine helps a lot of people, but some people can become hooked on it. That chance might be higher if you have a problem with drugs or alcohol, like abusing them or becoming hooked to them. Do what your doctor tells you to do with this medicine to keep from becoming hooked. Ask your nurse or doctor how you can find out more.

If your pain gets worse or doesn’t go away, you should tell your doctor.

What Tapentadol Can Do to You

You might get sick, throw up, have trouble going to the bathroom, feel dizzy, or be tired. If a side effect gets worse or lasts longer than expected, tell your doctor or pharmacist right away.

Eat fiber-rich foods, drink a lot of water, and work out to keep from getting constipated. Plus, you might need to take a pill. The drug shop worker you talk to will be able to tell you which cleanser is best for you.

Slowly rising from a sitting or lying down position can help you avoid getting dizzy or vertigo.

Think about the fact that your doctor gave you this medicine because they believed it would benefit you more than harm you. Plenty of people who take this medicine don’t have any big side effects.

If you experience any serious side effects, such as confusion, sleep apnea (stopping your breathing while you sleep), stomach or abdominal pain, trouble urinating, or signs that your adrenal glands aren’t working right, like losing your appetite, feeling tired all the time, or losing weight, you should tell your doctor right away.

Feeling faint, having seizures, breathing slowly or weakly, or being very sleepy and having trouble waking up? You should see a doctor right away.

This drug could raise the amount of serotonin in your body, which can sometimes cause serotonin syndrome or poisoning. When you take drugs that raise serotonin, the risk goes up. Tell your doctor or nurse about all the medicines you take (see How Drugs Work Together). You should see a doctor right away if you have a fast heartbeat, hallucinations, loss of balance, severe dizziness, severe nausea, vomiting, or diarrhea, muscles that shake, a fever you can’t explain, or feeling angry or stressed out for no reason.

It doesn’t happen very often that this drug will make you very allergic. But you should see a doctor right away if you have a strong allergic reaction, such as a rash, burning, or swelling (especially in the face, tongue, or throat), or if you can’t breathe or feel stable.

There are more side effects that could happen than are on this list. Talk to your chemist or doctor if you experience any other effects that aren’t on this list.

When you get sick in the US, you should talk to your doctor. Call 1-800-FDA-1088 or go to to tell the FDA about bad effects.

If something goes wrong in Canada, you should tell your doctor. You can call 1-866-234-2345 to let Health Canada know about bad effects.

Statements of Care and Attention

Be sure to let your doctor or nurse know if you are allergic to tapentadol or any other medicine before you take it. There may be inactive ingredients in this product that can make people allergic or cause other issues. To find out more, talk to your doctor.

Before taking this medicine, you should let your doctor or pharmacist know if you have any of the following: breathing problems (like asthma, sleep apnea, or chronic obstructive pulmonary disease (COPD)); gallbladder disease; kidney disease; liver disease; mental or mood disorders (like anxiety, depression, or suicidal thoughts); or a history of drug abuse or addiction in your family or yourself.

This drug could make you feel sleepy or dizzy. Both drinking and smoking weed can make you sleepy and dizzy. Before you are sure you can do something safely, don’t drive a car, move big things, or do anything else that needs your mind to be alert. You should not drink booze. Talk to your doctor if you use weed (cannabis).

You should let your dentist or doctor know about all the vitamins and medicines you take before surgery. This includes prescription drugs, over-the-counter medicines, and plant supplements.

There is a chance that people over 65 will be more sensitive to the side effects of this drug, especially forgetfulness, nausea, dizziness, and tiredness.

If you are pregnant, you should only take this medicine when you really need to. A child still in the womb could get hurt. Talk to your doctor about the health risks that come with the medicine. (Check out the part about being careful too.) We don’t know if this medicine goes into breast milk or not. It could be bad for babies who are being fed breast milk. If your baby seems sleepy for no reason, has trouble sucking, or has trouble breathing, you should call the doctor right away. Before you nurse, talk to your doctor.

Getting rid of Tapentadol

Keep it at room temperature, away from light and water, and make sure the humidity is the same as the room. Do not keep things in the bathroom. Do not give drugs to children or pets.

If someone doesn’t tell you otherwise, don’t flush or dump drugs in the toilet or bin. If you no longer need or want this thing, you should throw it away in the right way. You can read the Medication Guide, talk to your pharmacist, or call your local trash pickup service to find out more.

How drugs work

When two or more medicines combine, they can change how well they work or make you more likely to have major side effects. The drugs on this list don’t all go together. Give your doctor and pharmacist a list of all the medicines you take, including plant vitamins and prescription and over-the-counter medicines. Talk to your doctor before you start, stop, or change the amount of any drugs you are taking.

When mixed with naltrexone and mixed opioid agonist-antagonists like pentazocine, nalbuphine, and butorphanol, this drug can work together.

If you take this medicine along with MAO inhibitors, it could be very bad for you and even kill you. This medicine should not be taken by people who are already taking MAO inhibitors such as isocarboxazid, linezolid, methylene blue, moclobemide, phenelzine, procarbazine, rasagiline, safinamide, selegiline, or tranelcypromine. On top of that, you shouldn’t take most MAO inhibitors two weeks before you start treatment with this drug. You should talk to your doctor about when to start or stop taking this medicine.

Serotonin syndrome or poisoning are more likely to happen if you take more drugs that raise serotonin levels. Illegal drugs like MDMA (also called “ecstasy”), St. John’s Wort, and some antidepressants, like SNRIs (like duloxetine and venlafaxine) and SSRIs (like fluoxetine and paroxetine), are good examples. The chance of getting serotonin syndrome or being poisoned may rise if you start taking these drugs or if you take more of them.

People who take this medicine with other drugs that may also make you sleepy or have breathing problems may be more likely to have dangerous side effects like breathing that is slow or weak or being very sleepy or dizzy. Tell your doctor or pharmacist about any other medicines you’re taking, such as opioid painkillers or cough suppressants (like codeine or hydrocodone), alcohol, cannabis (marijuana), drugs to help you sleep or deal with anxiety (like alprazolam, lorazepam, or zolpidem), muscle relaxants (like carisoprodol or cyclobenzaprine), or antihistamines (like cetirizine or diphenhydramine).

If you take drugs for asthma or a cold or cough, make sure you read the labels of all of them because some of them may have ingredients that make you sleepy. It’s important to talk to your doctor before taking these drugs.

Some lab tests (amylase/lipase levels) might not work right if this drug is used. This could cause test results to be wrong. Make sure that all of your doctors and people who work in the lab know that you take this medicine.

Way too much

If you have naloxone on hand, give it to someone who has overdosed and is showing signs that they could die, like losing consciousness or having trouble breathing, before you call 911. Call a poison control center right away if the person is awake and doesn’t show any signs of poisoning. To reach the poison control center in your area, people in the US can call 1-800-222-1222. People in Canada can call the poison control center in their area. A slow heart rate, seizures, and coma are all signs of an overdose. As is breathing that is weak or slow.